Real-time investigation of dynamic protein crystallization in living cellsa)
نویسندگان
چکیده
R. Sch€ onherr, M. Klinge, J. M. Rudolph, K. Fita, D. Rehders, F. L€ ubber, S. Schneegans, I. V. Majoul, M. Duszenko, C. Betzel, A. Brandariz-Nu~ nez, J. Martinez-Costas, R. Duden, and L. Redecke Institute of Biology, Center for Structural and Cell Biology in Medicine, University of L€ ubeck, Ratzeburger Allee 160, 23562 L€ ubeck, Germany Institute of Biochemistry, Center for Structural and Cell Biology in Medicine, University of L€ ubeck, Ratzeburger Allee 160, 23562 L€ ubeck, Germany Interfaculty Institute of Biochemistry, University of T€ ubingen, Hoppe-Seyler-Strabe 4, 72076 T€ ubingen, Germany Institute of Biochemistry and Molecular Biology, University of Hamburg, c/o DESY, Notkestr. 85, 22603 Hamburg, Germany Department of Biochemistry and Molecular Biology, Centro de Investigaci on en Qu ımica Biol ogica y Materiales Moleculares (CIQUS), University Santiago de Compostela, 15782 Santiago de Compostela, Spain
منابع مشابه
Real-time investigation of dynamic protein crystallization in living cells.
X-ray crystallography requires sufficiently large crystals to obtain structural insights at atomic resolution, routinely obtained in vitro by time-consuming screening. Recently, successful data collection was reported from protein microcrystals grown within living cells using highly brilliant free-electron laser and third-generation synchrotron radiation. Here, we analyzed in vivo crystal growt...
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